Legacy
Strattice™ Reconstructive Tissue Matrix (TM) was launched in 2008 and has rapidly gained acceptance among U.S. doctors for use in challenging hernia repair and breast surgery cases. LifeCell™ is also the supplier of AlloDerm® Regenerative Tissue Matrix (RTM). These tissue matrices are both being used in a range of breast reconstruction and revision surgery cases.
The Breast Reconstruction Context
Since 2002, an increasing number of surgeons have been using LifeCell™ Tissue Matrices to overcome some of the challenges associated with breast reconstruction due to weak or inadequate tissue.
LifeCell™ Tissue Matrices have been used in over 45,000 breast reconstructions to help minimize the potential risk of complications associated with breast reconstruction due to weak or inadequate tissue.
They can reinforce thin tissue to support coverage where tissue has been aggressively resected and, by reinforcing the skin flap, may help the surgeon to control breast position and help redefine fold location by supporting the repair of inframammary and lateral folds.
Several published clinical studies have shown that there is a low complication rate associated with the use of AlloDerm® RTM in breast reconstruction postmastectomy.1 In addition, complication rates for acellular dermis-assisted breast reconstruction surgeries are similar to those reported in cases where acellular dermis was not used.2
AlloDerm® RTM leads to Strattice™ TM Development
Strattice™ TM was designed to perform mechanically and biologically similar to AlloDerm® RTM.
In animal studies, both AlloDerm® RTM and Strattice™ TM have demonstrated rapid revascularization and cell repopulation in as early as two weeks post-implantation and mature vascular structure at six months post-implantation.3
For more details about the science behind Strattice™ TM, request more information online.
1. Spear S, et al. Acellular dermis-assisted breast reconstruction. Aesth Plast Surg. 2008 May; 32(3):418-25.; Breuing K and Colwell A. Inferolateral AlloDerm® hammock for implant coverage in breast reconstruction. Ann Plast Surg. 2007;59(3):250-255.; Bindingnavele V, et al. Use of acellular cadaveric dermis and tissue expansion in postmastectomy breast reconstruction. Journal of Plastic, Reconstructive & Aesthetic Surgery. 2007;60:1214-18.; Salzberg C. Nonexpansive immediate breast reconstruction using human acellular tissue matrix graft (AlloDerm®). Ann Plast Surg. 2006;57(1):1-5.
2. Cordeiro P and McCarthy C. A single surgeon's 12-year experience with tissue expander/implant breast reconstruction: Part I. A prospective analysis of early complications. Plast and Recon Surgery. 2006 Sept;118(4):825-831.
3. Correlation of these results to results in humans is not established.
